A Component-Based Architecture for Automation of Protocol-Directed Therapy

Reference: Musen, M. A.; Tu, S. W.; Das, A. K.; & Shahar, Y. A Component-Based Architecture for Automation of Protocol-Directed Therapy. Knowledge Systems Laboratory, Medical Computer Science, 1995.

Abstract: The automation of protocol-based care requires reasoning about a patient's situation over time and about how the standard protocol plan can be adapted to address the patient's current clinical situation. The EON architecture brings together (1) a skeletal-planning reasoning method, ESPR, that can determine appropriate clinical interventions by instantiating an abstract protocol specification, (2) a temporal-reasoning system, RESUME, that can infer from time-stamped patient data higher-level, interval-based concepts, and (3) a historical database system, Chronus, that can perform temporal queries on a database of interval-based patient descriptions. The modular problem-solving elements of EON operate on knowledge bases of clinical protocols that clinicians enter into domain-specific knowledge-acquisition tools generated by the PROTEGE-II system. The EON architecture provides an integrated framework for development, execution, and maintenance of clinical-protocol knowledge bases.

Notes: Updated April.

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